Bioactive Molecules (GC-MS) of Endophytic Fungi, Xylaria from Nyctanthes arbor-trists (Linn)

Abstract

This study deals with isolation and identification (GC-MS) of bioactive molecules from an
endophytic fungus isolated from a traditional medicinal shrub Nyctanthes arbor-trists (Linn). Total 11 compounds
were identified from the isolated fungal extract. On the basis of study of macroscopic and microscopic characters
and ITS sequencing, isolated endophytic fungus was identified as Xylaria. Secondary metabolites isolated
from Xylaria were screened for antimicrobial assay against three pathogenic bacteria. Crude extract of Xylaria
was demonstrated strong inhibitor of three pathogenic bacteria Micrococcus luteus (clear zone 68.2 mm),
Citrobacter freundii (clear zone of 59.16 mm) and Chromobacterium violaceum (clear zone 39.96 mm). Production
of hydrolyzing enzymes like amylase and lipase from Xylaria was also detected.