Total Phenolic Content, Antioxidant and Antimicrobial Activity of Fumaria indica (Hausskn.) Pugsley

Abstract

The comprised investigation examines total phenolic content, antioxidant activity and antimicrobial activity in ethanolic extract fraction of Fumaria indica. An in vitro evaluation model utilizing a β-carotene bleaching assay and DPPH free radical scavenging test was employed for the assessment of antioxidant potential of the plant extract. A modified Folin-Ciocalteu method used for total phenolic content (TPC) determination in this study estimated the TPC in F. indica to be as high as 11.42 mg/g of extract. The antioxidant potential of the plant extract was observed 54.85 % measured as total antioxidant activity (AA %), with reference to the BHA (92.74 %) and BHT (89.34 %) used as standards. The results of free radical scavenging property depicted the DPPH radical scavenged by the extract of F. indica were 48.65 %. It had antimicrobial activity against eleven bacteria and nine fungi determined using disc diffusion method. The findings of this research adjudged the extract of F. indica a rich source of natural antioxidant and endowed with antimicrobial activity