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Total Phenolic Content, Antioxidant and Antimicrobial Activity of Fumaria indica (Hausskn.) Pugsley

Abstract:

The comprised investigation examines total phenolic content, antioxidant activity and
antimicrobial activity in ethanolic extract fraction of Fumaria indica. An in vitro evaluation model utilizing
a β-carotene bleaching assay and DPPH free radical scavenging test was employed for the assessment of
antioxidant potential of the plant extract. A modified Folin-Ciocalteu method used for total phenolic content
(TPC) determination in this study estimated the TPC in F. indica to be as high as 11.42 mg/g of extract. The
antioxidant potential of the plant extract was observed 54.85 % measured as total antioxidant activity (AA
%), with reference to the BHA (92.74 %) and BHT (89.34 %) used as standards. The results of free radical
scavenging property depicted the DPPH radical scavenged by the extract of F. indica were 48.65 %. It had
antimicrobial activity against eleven bacteria and nine fungi determined using disc diffusion method. The
findings of this research adjudged the extract of F. indica a rich source of natural antioxidant and endowed
with antimicrobial activity.