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Advancing Open Science for more than 25 years

Studies on the Anti-inflammatory and Analgesic Activities of Allium stracheyi, A Medicinal Plant of Alpine Himalayas of Uttarakhand

Abstract: In the present study, Allium stracheyi leaves were explored for their anti-inflammatory and
analgesic potential on experimental model and compared to standard drugs. The results showed that methanolic
extract show significant reduction in inflammation i.e. 61 % (100 mg/kg) (p< 0.5) as compared to the standard
drug Diclofenac sodium suspension in 0.1 % Tween 80 (10 mg/kg body weight) as well as the highest analgesic
potential i.e. 64.62 % (100 mg/kg) as compared to aspirin 68.62 % at 25 mg/kg body weight. Thus, methanolic
extract of the plant can be explored for its anti-inflammatory and analgesic potential which has not been
reported so far. The plant extract showed a relative low toxicity hence justifies the folkloric use of plant by the
local people in Western Himalayan region for curing inflammation and painful conditions.